Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346437 | 0.83 | GPR35 (0.51) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL19175047 | 0.80 | ALDH1A1 (0.47) | ALOX12MAPTHPGDPOLBALDH1A1 | |
| SCHEMBL8170826 | 0.80 | GPR35 (0.49) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL10819607 | 0.80 | GPR35 (0.51) | GPR35SNCAALOX15ALOX12SIRT6 | |
| Hydrochloric Acid SCHEMBL11339240 | 0.78 | IDO1 (0.56) | GPR35SNCAALOX15SIRT6MAPT | |
| SCHEMBL4962677 | 0.77 | GPR35 (0.56) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL28917367 | 0.77 | GPR35 (0.49) | GPR35SNCAALOX15SIRT6MAPT | |
| SCHEMBL27671999 | 0.77 | GPR35 (0.49) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL9198508 | 0.77 | SNCA (0.62) | GPR35SNCAALOX15SIRT6MAPT | |
| SCHEMBL28917368 | 0.76 | GPR35 (0.47) | GPR35SNCAALOX15SIRT6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222381-B2 | Derivatives of monosaccharides for drug discovery | ALCHEMIA LIMITED (AU) | 2012-07-17 | — | — | US | disclosed |