SCHEMBL23466752 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CTSS	P25774	10/20	0.42

▸	CTSK	P43235	9/20	0.42

▸	CTSB	P07858	3/20	0.40

▸	CTSL	P07711	1/20	0.40

▸	SCN9A	Q15858	5/20	0.40

▸	AKT1	P31749	1/20	0.40

▸	PPARG	P37231	1/20	0.37

▸	PPARA	Q07869	1/20	0.37

▸	HRH2	P25021	1/20	0.37

▸	HRH1	P35367	1/20	0.37

▸	CYP3A4	P08684	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28974565	0.88	HDAC8 (0.44)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL28974567	0.88	HDAC8 (0.44)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466548	0.84	CTSS (0.40)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466423	0.83	CTSS (0.40)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466767	0.83	CTSS (0.43)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466435	0.82	CTSS (0.39)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466753	0.82	HDAC8 (0.42)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23486735	0.82	HDAC8 (0.42)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466563	0.80	SCN9A (0.45)	CTSSCTSKCTSBCTSLSCN9A
SCHEMBL23466774	0.80	CTSS (0.40)	CTSSCTSKCTSBCTSLSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021110076-A1	OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE	深圳信立泰药业股份有限公司	2021-06-10	—	—	WO	disclosed