Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974567 | 1.00 | HDAC8 (0.44) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL23486735 | 0.94 | HDAC8 (0.42) | HDAC8SCN9ACTSSCTSKL3MBTL1 | |
| SCHEMBL23466753 | 0.94 | HDAC8 (0.42) | HDAC8SCN9ACTSSCTSKL3MBTL1 | |
| SCHEMBL28974568 | 0.91 | HDAC8 (0.46) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL28974559 | 0.91 | HDAC8 (0.46) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL28974517 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL28974412 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL28974522 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL28974406 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1CTSSCTSK | |
| SCHEMBL23466752 | 0.88 | CTSS (0.42) | SCN9ACTSSCTSKAKT1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |