Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.60 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758057 | 0.88 | CTSS (0.74) | CTSSCTSKCTSBACEPTPN1 | |
| SCHEMBL30655726 | 0.88 | CTSS (0.74) | CTSSCTSKCTSBACEPTPN1 | |
| SCHEMBL30829402 | 0.88 | CTSS (0.74) | CTSSCTSKCTSBACEPTPN1 | |
| SCHEMBL1073538 | 0.88 | CTSS (0.74) | CTSSCTSKCTSBACEPTPN1 | |
| SCHEMBL3553426 | 0.88 | CTSS (0.74) | CTSSCTSKCTSBACEPTPN1 | |
| SCHEMBL2333358 | 0.88 | CTSS (0.74) | CTSSCTSKCTSBACEPTPN1 | |
| SCHEMBL20905314 | 0.79 | CTSS (0.71) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL27350854 | 0.79 | CTSS (0.71) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL21946642 | 0.78 | CTSS (0.69) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL25183126 | 0.78 | CTSB (0.49) | CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021112251-A1 | AZETIDINE SULFONAMIDE COMPOUND | 第一三共株式会社 | 2021-06-10 | — | — | WO | disclosed |