Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | LTK | P29376 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725339 | 1.00 | TOP2A (0.44) | TOP2ACCR1CCR8CCR5L3MBTL1 | |
| SCHEMBL19452852 | 0.94 | NR1H2 (0.42) | TOP2ACCR1CCR8CCR5L3MBTL1 | |
| Bathocuproine SCHEMBL29351092 | 0.88 | CRHR1 (0.48) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL20526077 | 0.88 | CRHR1 (0.48) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL29356702 | 0.88 | CRHR1 (0.48) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL36914 | 0.88 | CRHR1 (0.48) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL5398100 | 0.87 | CRHR1 (0.47) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL38659029 | 0.87 | CRHR1 (0.47) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL28523242 | 0.87 | CRHR1 (0.47) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 | |
| Bathocuproine SCHEMBL29080447 | 0.87 | CRHR1 (0.47) | L3MBTL1CRHR1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361444-A1 | MATERIALS | Lomox Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| WO-2009103952-A1 | MATERIALS | LOMOX LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |