SCHEMBL725339

SCHEMBL725339

Cc1cc(-c2ccccc2)c2ccc3c(-c4ccccc4)ccnc3c2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 2/20 0.44
CCR1 P32246 3/20 0.41
CCR8 P51685 3/20 0.41
CCR5 P51681 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CRHR1 P34998 1/20 0.41
MAP4K4 O95819 2/20 0.41
IGF1R P08069 2/20 0.41
LTK P29376 2/20 0.41
KDR P35968 2/20 0.41
MAP2K2 P36507 2/20 0.41
MAPK8 P45983 2/20 0.41
CLK2 P49760 2/20 0.41
CDK7 P50613 2/20 0.41
CDK9 P50750 2/20 0.41
CDK5 Q00535 2/20 0.41
MAP2K1 Q02750 2/20 0.41
ACVR1 Q04771 2/20 0.41
PTK2 Q05397 2/20 0.41
NTRK3 Q16288 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bathocuproine SCHEMBL2346807 1.00 TOP2A (0.44) TOP2ACCR1CCR8CCR5L3MBTL1
SCHEMBL19452852 0.94 NR1H2 (0.42) TOP2ACCR1CCR8CCR5L3MBTL1
Bathocuproine SCHEMBL29351092 0.88 CRHR1 (0.48) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL20526077 0.88 CRHR1 (0.48) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL29356702 0.88 CRHR1 (0.48) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL36914 0.88 CRHR1 (0.48) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL5398100 0.87 CRHR1 (0.47) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL38659029 0.87 CRHR1 (0.47) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL28523242 0.87 CRHR1 (0.47) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2
Bathocuproine SCHEMBL29080447 0.87 CRHR1 (0.47) L3MBTL1CRHR1KDM4EALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105742395-B Up-conversion device and photodetector with gain (EC) 佛罗里达大学研究基金会有限公司 2019-02-15 CN claimed
CN-105990529-A Organic light emitting device 三星显示有限公司 2016-10-05 CN claimed
WO-2024132695-A1 CONVERSION OF A BIOMASS-DERIVED HYDROCARBON FEEDSTOCK TO PRODUCE ADIPIC ACID IFP Energies Nouvelles (FR) 2024-06-27 WO disclosed
CN-117677625-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-03-08 CN disclosed
WO-2022011991-A9 LIGHT-EMITTING DEVICE AND PREPARATION METHOD THEREFOR TCL科技集团股份有限公司 2022-03-10 WO disclosed
US-20210028368-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-28 US disclosed
CN-106132923-B Oligoaniline derivative, charge-transporting varnish and organic electroluminescent device 日产化学工业株式会社 2019-11-15 CN disclosed
CN-110383521-A Organic electric-field light-emitting element 学校法人关西学院 2019-10-25 CN disclosed
CN-110291652-A Organic electroluminescent element 学校法人关西学院 2019-09-27 CN disclosed
CN-110197876-A Electronic equipment and lighting apparatus 三星显示有限公司 2019-09-03 CN disclosed
CN-110028523-A Polycyclc aromatic compound and its polymer, organic element material, organic electric-field light-emitting element, display device or lighting device 学校法人关西学院 2019-07-19 CN disclosed
WO-2009029727-A1 CANNABINOID RECEPTOR TARGETED AGENT VANDERBILT UNIVERSITY (US) 2009-03-05 WO disclosed
US-20080315753-A1 PHOSPHORESCENT OLED HAVING DOUBLE EXCITON-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC 2008-12-25 US disclosed
US-20080315753-A1 PHOSPHORESCENT OLED HAVING DOUBLE EXCITON-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC 2008-12-25 US disclosed
WO-2008150943-A1 HOLE TRANSPORT MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-11 WO disclosed
US-20080241873-A1 MULTI-USE MULTIMODAL IMAGING CHELATES BORNHOP DARRYL J 2008-10-02 US disclosed
US-20080241074-A1 MULTI-USE MULTIMODAL IMAGING CHELATES VANDERBILT UNIVERSITY 2008-10-02 US disclosed
US-7338651-B2 Multi-use multimodal imaging chelates TEXAS TECH UNIVERSITY SYSTEM (US) 2008-03-04 US disclosed
EP-1770415-A1 CONDENSER FILM, LIQUID CRYSTAL PANEL, BACKLIGHT AND METHOD FOR PRODUCING CONDENSER FILM Kuraray Co., Ltd., Kurashiki Plant (JP) 2007-04-04 EP disclosed
US-20070037983-A1 Phenanthroline derivative compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037983-A1 Phenanthroline derivative compound POP1, PABPC1, NAP1L1 TOP2A 550/4885CCR1 2669/4885CCR8 4103/4885
US-20210028368-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME EHD1, HVCN1, CRY1 TOP2A 1947/4885CCR1 282/4885CCR8 1767/4885
US-20080241074-A1 MULTI-USE MULTIMODAL IMAGING CHELATES PCNA, CLTC, CLTB TOP2A 270/4885CCR1 1040/4885CCR8 672/4885
US-20080241873-A1 MULTI-USE MULTIMODAL IMAGING CHELATES PCNA, CLTC, CLTB TOP2A 270/4885CCR1 1040/4885CCR8 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.