Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174728 | 0.89 | CYP4F2 (0.56) | CYP4F2CYP4A11TSHRSLC7A5LOXL2 | |
| SCHEMBL23471232 | 0.88 | CYP4F2 (0.53) | CYP4F2CYP4A11TSHRSLC7A5LOXL2 | |
| SCHEMBL17798298 | 0.87 | TSHR (0.61) | CYP4F2CYP4A11TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL19634285 | 0.86 | LOXL2 (0.69) | CYP4F2CYP4A11TSHRSLC7A5LOXL2 | |
| SCHEMBL23471000 | 0.85 | SLC7A5 (0.65) | CYP4F2CYP4A11TSHRSLC7A5LOXL2 | |
| SCHEMBL9770912 | 0.83 | CYP4F2 (0.57) | CYP4F2CYP4A11TSHRSMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27753064 | 0.83 | L3MBTL1 (0.54) | TSHRSMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL3009859 | 0.82 | CYP4F2 (0.55) | CYP4F2CYP4A11TSHRSLC7A5LOXL2 | |
| SCHEMBL128387 | 0.82 | CYP4F2 (0.72) | CYP4F2CYP4A11TSHRLOXL2SMN1; SMN2 | |
| SCHEMBL13974641 | 0.82 | TSHR (0.56) | CYP4F2CYP4A11TSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |