Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472305 | 0.90 | TLR7 (0.44) | TLR7TLR8CYP1A2 | |
| SCHEMBL15470063 | 0.88 | TLR7 (0.61) | TLR7TLR8CYP1A2 | |
| SCHEMBL17035560 | 0.87 | TLR7 (0.54) | TLR7TLR8CYP1A2IP6K1PDE4A | |
| SCHEMBL23472210 | 0.87 | MTNR1B (0.47) | TLR7TLR8 | |
| SCHEMBL13195680 | 0.87 | FLT3 (0.41) | TLR7TLR8CYP1A2 | |
| SCHEMBL23472630 | 0.86 | MAPT (0.39) | TLR7TLR8CYP1A2 | |
| SCHEMBL20219401 | 0.85 | ALDH1A1 (0.43) | TLR7TLR8CYP1A2 | |
| SCHEMBL20219660 | 0.83 | TLR7 (0.49) | TLR7TLR8CYP1A2 | |
| SCHEMBL23472466 | 0.83 | CYP1A2 (0.45) | TLR7TLR8CYP1A2GBA1 | |
| SCHEMBL23472163 | 0.83 | TLR7 (0.49) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |