Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123641 | 0.86 | P2RX3 (0.41) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL20413303 | 0.81 | TLR7 (0.37) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL18644351 | 0.79 | TLR7 (0.49) | TLR7TLR8KCNH2 | |
| SCHEMBL18644353 | 0.79 | TLR7 (0.37) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL20219553 | 0.77 | TLR7 (0.44) | TLR7TLR8KCNH2 | |
| SCHEMBL19274182 | 0.76 | TLR7 (0.43) | TLR7TLR8KCNH2 | |
| SCHEMBL15469944 | 0.76 | TLR7 (0.43) | TLR7TLR8KCNH2 | |
| SCHEMBL20386702 | 0.76 | TLR7 (0.46) | TLR7TLR8KCNH2 | |
| SCHEMBL20219720 | 0.75 | TLR7 (0.46) | TLR7TLR8KCNH2 | |
| SCHEMBL23472270 | 0.73 | TLR8 (0.41) | TLR7TLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |