Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminosalicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.96 |
| ▸ | MAPT | P10636 | 5/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.96 |
| ▸ | GAA | P10253 | 2/20 | 0.96 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.96 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TNF | P01375 | 1/20 | 0.67 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminosalicylic Acid SCHEMBL28535200 | 0.98 | ALDH1A1 (0.92) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL3333393 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL2262 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL29450213 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL30337954 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL564092 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL1047422 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL28886739 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL11788850 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL29030136 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113249502-A | Related gene, method, primer group and kit for mycobacterium tuberculosis complex flora identification and drug resistance detection | 上海康黎诊断技术有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-106512487-B | A kind of polysiloxane-based antifoaming agent of 4- amino-2-hydroxybenzoic acids sodium synergy | 江门市冠达化工科技有限公司 | 2018-07-27 | — | — | CN | claimed |
| CN-106512487-A | 4-amino-2-sodium hydroxybenzoate synergistic polysiloxane defoaming agent | 佛山迅拓奥科技有限公司 | 2017-03-22 | — | — | CN | claimed |
| US-20150329728-A1 | AMINE COMPOUNDS AND THEIR USE AS ZERO OR LOW VOC NEUTRALIZERS | ANGUS CHEMICAL COMPANY (US) | 2015-11-19 | — | — | US | claimed |
| EP-2935477-A1 | AMINE COMPOUNDS AND THEIR USE AS ZERO OR LOW VOC NEUTRALIZERS | ANGUS Chemical Company (US) | 2015-10-28 | — | — | EP | claimed |
| WO-2014099213-A1 | AMINE COMPOUNDS AND THEIR USE AS ZERO OR LOW VOC NEUTRALIZERS | ANGUS CHEMICAL COMPANY (US) | 2014-06-26 | — | — | WO | claimed |
| CN-1134278-A | Aerosol for preventing and curing pulmonary tuberculosis and its preparing method and synergy method | CONG FANZI (CN) | 1996-10-30 | — | — | CN | claimed |
| CN-116459749-A | Continuous manufacturing device for sodium p-aminosalicylate | 辽宁药联制药有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-113249502-A | Related gene, method, primer group and kit for mycobacterium tuberculosis complex flora identification and drug resistance detection | 上海康黎诊断技术有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-112920225-A | Water-soluble iron carbonyl compound containing sulfonate, and preparation method and application thereof | 嘉兴学院 | 2021-06-08 | — | — | CN | disclosed |
| US-10865421-B2 | Acyltransferases and methods of using | NUTECH VENTURES (US) | 2020-12-15 | — | — | US | disclosed |
| US-10722562-B2 | Combinatorial analysis and repair | IMMUDEX APS (DK) | 2020-07-28 | — | — | US | disclosed |
| CN-110257535-A | Mycobacterium tuberculosis (Mtb) MLVA genotyping kit | 大理大学 | 2019-09-20 | — | — | CN | disclosed |
| EP-0576792-A2 | Plasmids and process for producing recombinant desulphatohirudin HV-1 peptide | BIOGAL GYOGYSZERGYAR RT. (HU) | 1994-01-05 | — | — | EP | disclosed |
| EP-0388356-A2 | Ultraviolet absorbing lenses and methods of making the same | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |
| US-4933330-A | PSORIASIS | DAK-LABORATORIET (DK) | 1990-06-12 | — | — | US | disclosed |
| US-4924010-A | GASTROINTESTINAL DISORDERS | RORER PHARMACEUTICAL CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4859683-A | Certain benzoxepins and their pharmaceutical compositions and methods | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| US-4857517-A | Quinuclidyl benzoxepins as 5-HT3 antagonists | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0291159-A2 | Aminosalicylic-acid derivatives for the treatment of psoriasis | DAK-LABORATORIET A/S (DK) | 1988-11-17 | — | — | EP | disclosed |