Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.56 |
| ▸ | DRD3 | P35462 | 12/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 3/20 | 0.48 |
| ▸ | DRD5 | P21918 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10247150 | 0.88 | DRD3 (0.62) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL629321 | 0.88 | OPRK1 (0.62) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL18566685 | 0.88 | OPRK1 (0.62) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL24540244 | 0.88 | OPRK1 (0.62) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL10247281 | 0.88 | DRD3 (0.62) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL8408108 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL21632258 | 0.77 | DRD2 (0.54) | DRD2DRD3OPRK1DRD4DRD1 | |
| SCHEMBL10382832 | 0.76 | OPRK1 (0.62) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL6211308 | 0.76 | DRD2 (0.49) | DRD2DRD3OPRK1DRD4MEN1 | |
| SCHEMBL6211310 | 0.76 | OPRK1 (0.49) | DRD2DRD3OPRK1DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021109713-A1 | USE AND PHARMACEUTICAL COMPOSITION OF PHENYLISOXAZOLYL METHYLENE-NAPHTHALENE-ETHER DERIVATIVES | GANNEX PHARMA CO., LTD. (CN) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021108974-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | GANNEX PHARMA CO., LTD (CN) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021109712-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | GANNEX PHARMA CO., LTD. (CN) | 2021-06-10 | — | — | WO | disclosed |