Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 13/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23461135 | 0.92 | F2 (0.48) | FPR2F2PRSS1F10PLAT | |
| SCHEMBL5483486 | 0.84 | F2 (0.62) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5856832 | 0.80 | F2 (0.59) | F2F10 | |
| SCHEMBL12670271 | 0.79 | F2 (0.39) | FPR2F2F10 | |
| SCHEMBL4898740 | 0.73 | F2 (0.63) | F2PRSS1F10PLATPRSS2 | |
| SCHEMBL23460848 | 0.73 | FPR2 (0.40) | FPR2LMNATSHR | |
| SCHEMBL5475081 | 0.72 | KDM4E (0.47) | F2PRSS1 | |
| SCHEMBL23460615 | 0.72 | F2 (0.61) | F2PRSS1F10PLATPRSS2 | |
| SCHEMBL5474418 | 0.71 | TLR9 (0.42) | FPR2LMNATSHR | |
| SCHEMBL12636573 | 0.70 | FPR2 (0.46) | FPR2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113686-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |