SCHEMBL23474359

SCHEMBL23474359

Cc1ccc(OC(C)(C)c2ccc(OC(C)(C)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ACHE P22303 3/20 0.44
RELA Q04206 1/20 0.40
MAPT P10636 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 1/20 0.38
TEAD4 Q15561 1/20 0.38
ALDH1A1 P00352 3/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 2/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
HPGD P15428 1/20 0.34
MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19928041 1.00 TSHR (0.50) TSHRACHERELAMAPTNPC1
SCHEMBL21191439 0.92 MAPK1 (0.50) TSHRACHEMAPTTDP1CYP3A4
SCHEMBL18405602 0.90 TEAD4 (0.55) TSHRACHERELAMAPTNPC1
SCHEMBL21191319 0.90 ACHE (0.50) TSHRACHEMAPTNPC1RAB9A
SCHEMBL9707201 0.89 MAPK1 (0.52) TSHRACHERELAALDH1A1LMNA
SCHEMBL21090929 0.87 ACHE (0.54) TSHRACHERELAMAPTNPC1
SCHEMBL19928038 0.83 MAPT (0.50) TSHRMAPTNPC1RAB9ATDP1
SCHEMBL22399103 0.81 CYP2A6 (0.48) TSHRNPC1RAB9ATDP1CYP3A4
SCHEMBL19359712 0.81 GAA (0.50) TSHRACHEMAPTNPC1RAB9A
SCHEMBL11999007 0.81 ALDH1A1 (0.42) TSHRACHEMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210171710-A1 POLYARYLENE ETHER KETONE RESIN AND PRODUCTION METHOD THEREFOR, AND MOLDED ARTICLE DIC CORPORATION (JP) 2021-06-10 US disclosed