SCHEMBL2347459

SCHEMBL2347459

C[Sn](C)(OCCc1ccccc1)O[Sn](C)(C)OCCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
IDO1 P14902 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2698151 0.91 CA1 (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL2330108 0.83 CA1 (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL2348857 0.78 TSHR (0.48) CA1CA2CA9IDO1RAB9A
SCHEMBL2347598 0.73 SIGMAR1 (0.40) IDO1NPC1RAB9AKCNH2
SCHEMBL2325089 0.72 CA1 (0.42) CA1CA2CA9IDO1NPC1
SCHEMBL2324422 0.72 CA1 (0.42) CA1CA2CA9IDO1NPC1
SCHEMBL2326215 0.72 SIGMAR1 (0.42) IDO1NPC1RAB9AKCNH2
SCHEMBL2326189 0.72 SIGMAR1 (0.42) IDO1NPC1RAB9AKCNH2ALDH1A1
SCHEMBL2345050 0.71 SIGMAR1 (0.41) IDO1NPC1RAB9AKCNH2
SCHEMBL2330784 0.71 SIGMAR1 (0.41) IDO1NPC1RAB9AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535896-B1 PROCESS FOR PRODUCING CARBONIC ESTER ASAHI KASEI CHEMICALS CORP (JP) 2015-10-07 EP disclosed
EP-1760085-B1 PROCESS FOR PRODUCTION OF ALKYLTIN ALKOXIDES ASAHI KASEI CHEMICALS CORP (JP) 2014-02-26 EP disclosed
US-8168812-B2 Process for producing alkyl tin alkoxide compound and process for producing carbonic acid ester using said compound ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-05-01 US disclosed
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
US-7541482-B2 Process for production of alkyltin alkoxides ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-06-02 US disclosed
US-20080275262-A1 Process for Production of Alkyltin Alkoxides ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-11-06 US disclosed
US-7446218-B2 Process for producing carbonic ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-11-04 US disclosed
US-20070055042-A1 Method for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
EP-1760085-A1 PROCESS FOR PRODUCTION OF ALKYLTIN ALKOXIDES Asahi Kasei Chemicals Corporation (JP) 2007-03-07 EP disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed
US-20050240045-A1 Process for producing carbonic ester ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-10-27 US disclosed
EP-1535896-A1 PROCESS FOR PRODUCING CARBONIC ESTER Asahi Kasei Chemicals Corporation (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240045-A1 Process for producing carbonic ester ALKBH3, CYP4A11, CYP2E1 CA1 163/4885CA2 396/4885CA9 49/4885
US-20080275262-A1 Process for Production of Alkyltin Alkoxides ALK, MOGAT2, SOAT2 CA1 4399/4885CA2 4090/4885CA9 2647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.