Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896509 | 0.97 | TSHR (0.48) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL10793051 | 0.95 | DNM1 (0.48) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL11554162 | 0.95 | DNM1 (0.48) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL11416179 | 0.95 | DNM1 (0.48) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL606730 | 0.95 | TSHR (0.50) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL10792995 | 0.90 | TSHR (0.46) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL4562415 | 0.87 | TSHR (0.57) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL870314 | 0.86 | SMN1; SMN2 (0.46) | TSHRDNM1CA12CA1CA9 | |
| SCHEMBL3341604 | 0.84 | — | — | |
| SCHEMBL4732004 | 0.83 | CA12 (0.40) | TSHRCA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021111464-A1 | A PROCESS FOR THE PREPARATION OF HIGHLY PURE VALSARTAN | HARMAN FINOCHEM LIMITED (IN) | 2021-06-10 | — | — | WO | disclosed |
| US-20170012226-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170012226-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | TBL2, TBL3, TLL1 | TSHR 25/4885DNM1 4309/4885CA12 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.