Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.59 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480422 | 0.93 | STING1 (0.64) | STING1ACHE | |
| SCHEMBL21405886 | 0.85 | STING1 (0.79) | STING1ACHE | |
| SCHEMBL23480284 | 0.84 | STING1 (0.79) | STING1ACHE | |
| SCHEMBL23461386 | 0.84 | STING1 (0.79) | STING1ACHE | |
| SCHEMBL21405933 | 0.84 | STING1 (0.62) | STING1ACHE | |
| SCHEMBL24175699 | 0.84 | STING1 (0.62) | STING1ACHE | |
| SCHEMBL24175170 | 0.81 | STING1 (0.65) | STING1ACHE | |
| SCHEMBL23480855 | 0.81 | STING1 (0.59) | STING1 | |
| SCHEMBL21452607 | 0.80 | STING1 (0.64) | STING1ACHE | |
| SCHEMBL21452706 | 0.78 | STING1 (0.80) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |