Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A3 | P40879 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472100 | 0.87 | SLC26A3 (0.48) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL23472098 | 0.79 | CYP1A1 (0.44) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL23472102 | 0.79 | SLC26A3 (0.39) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL23472064 | 0.78 | SLC26A3 (0.42) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL1985951 | 0.77 | POLB (0.53) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL23480274 | 0.75 | SLC26A3 (0.43) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL8572156 | 0.72 | POLB (0.58) | SLC26A3POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL23480253 | 0.72 | CTDSP1 (0.45) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL23480250 | 0.71 | CTDSP1 (0.45) | DUSP3PTPN5PTPN11CTDSP1MEN1 | |
| SCHEMBL23472052 | 0.71 | CYP1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110834-A2 | COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING | ETH ZURICH (CH) | 2021-06-10 | — | — | WO | disclosed |