Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A3 | P40879 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480275 | 0.91 | KDM4E (0.44) | KMT2A | |
| SCHEMBL23472098 | 0.84 | CYP1A1 (0.44) | SLC26A3POLBCTDSP1DUSP3PTPN5 | |
| SCHEMBL23472064 | 0.83 | SLC26A3 (0.42) | SLC26A3POLBCTDSP1DUSP3PTPN5 | |
| SCHEMBL23472100 | 0.79 | SLC26A3 (0.48) | SLC26A3POLBCTDSP1DUSP3PTPN5 | |
| SCHEMBL23472052 | 0.76 | CYP1A1 (0.43) | — | |
| SCHEMBL23471908 | 0.75 | KDM4E (0.42) | — | |
| SCHEMBL1985951 | 0.75 | POLB (0.53) | SLC26A3POLBCTDSP1DUSP3PTPN5 | |
| SCHEMBL23480802 | 0.75 | SLC26A3 (0.46) | SLC26A3POLBCTDSP1DUSP3PTPN5 | |
| SCHEMBL23480242 | 0.73 | CYP2D6 (0.40) | SLC26A3CTDSP1DUSP3PTPN5PTPN11 | |
| SCHEMBL23472102 | 0.70 | SLC26A3 (0.39) | SLC26A3POLBCTDSP1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110834-A2 | COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING | ETH ZURICH (CH) | 2021-06-10 | — | — | WO | disclosed |