Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.69 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.66 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.61 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947211 | 1.00 | ENPP2 (0.69) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL1296442 | 0.99 | ENPP2 (0.71) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL1296633 | 0.99 | ENPP2 (0.71) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL1295914 | 0.99 | ENPP2 (0.71) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL1296721 | 0.99 | ENPP2 (0.71) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL1296948 | 0.91 | LPAR1 (0.80) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL234397 | 0.91 | ENPP2 (0.56) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL3410348 | 0.91 | ENPP2 (0.56) | ENPP2LPAR1LPAR3SMN1; SMN2LPAR4 | |
| SCHEMBL1899147 | 0.91 | PRKCA (0.62) | ENPP2LPAR1LPAR3RECQLBLM | |
| SCHEMBL1903151 | 0.91 | PRKCA (0.62) | ENPP2LPAR1LPAR3RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578237-A1 | Compositions and methods for enhancing contrast in imaging | Marval Biosciences, Inc. (US) | 2013-04-10 | — | — | EP | disclosed |
| EP-2410990-A1 | COMPOSITIONS AND METHODS FOR ENHANCING CONTRAST IN IMAGING | Marval Biosciences, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20120003159-A1 | COMPOSITIONS AND METHODS FOR ENHANCING CONTRAST IN IMAGING | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2010107990-A1 | COMPOSITIONS AND METHODS FOR ENHANCING CONTRAST IN IMAGING | MARVAL BIOSCIENCES, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-7785568-B2 | Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography | MARVAL BIOSCIENCES, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080131369-A1 | Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography | MARVEL THERAPEUTICS (US) | 2008-06-05 | — | — | US | disclosed |
| US-20070212303-A1 | Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography | MARVAL PHARMA, INC. | 2007-09-13 | — | — | US | disclosed |