Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.51 |
| ▸ | TUBB | P07437 | 6/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459076 | 0.84 | CACNA1H (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29919434 | 0.84 | CACNA1H (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15584882 | 0.70 | CACNA1H (0.53) | SMN1; SMN2CACNA1GRAD52KMT2ACACNA1H | |
| SCHEMBL24670085 | 0.69 | RAD52 (0.63) | SMN1; SMN2RAD52UBE2NKMT2AALDH1A1 | |
| SCHEMBL19494569 | 0.68 | SMN1; SMN2 (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8192405 | 0.68 | ALDH1A1 (0.59) | RAD52UBE2NKMT2ALMNACYP1A2 | |
| SCHEMBL23731882 | 0.68 | CACNA1H (0.53) | SMN1; SMN2CACNA1HTSHRMAPK10ALDH1A1 | |
| SCHEMBL15584671 | 0.68 | CACNA1H (0.53) | SMN1; SMN2CACNA1GKMT2ACACNA1HTSHR | |
| SCHEMBL15243340 | 0.68 | CACNA1H (0.53) | SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL30103105 | 0.68 | CACNA1H (0.53) | SMN1; SMN2CACNA1HTSHRMAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021111124-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2021-06-10 | — | — | WO | disclosed |