Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.63 |
| ▸ | UBE2N | P61088 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670060 | 0.88 | RAD52 (0.59) | RAD52UBE2NIDO1KMT2AMAPT | |
| SCHEMBL7072252 | 0.78 | RAD52 (0.59) | RAD52UBE2NIDO1MAPTPKM | |
| SCHEMBL22361963 | 0.78 | TDP1 (0.76) | RAD52IDO1KMT2APKMTDP1 | |
| SCHEMBL31285595 | 0.78 | TDP1 (0.76) | RAD52IDO1KMT2APKMTDP1 | |
| SCHEMBL6159261 | 0.77 | F2 (0.60) | RAD52UBE2NMAPTPKMTDP1 | |
| SCHEMBL24345987 | 0.77 | RAD52 (0.49) | RAD52UBE2NIDO1PKMTDP1 | |
| SCHEMBL6159269 | 0.76 | POLB (0.70) | RAD52UBE2NKMT2AMAPTPKM | |
| SCHEMBL12686275 | 0.75 | PLAU (0.58) | RAD52UBE2NKMT2AMAPTPKM | |
| SCHEMBL1206200 | 0.74 | RAD52 (0.51) | RAD52UBE2NKMT2AMAPTPKM | |
| Hydrochloric Acid SCHEMBL23201245 | 0.73 | PLAU (0.56) | RAD52UBE2NKMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |