Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970192 | 0.76 | MEN1 (0.36) | PNMTNOS3NOS2NOTUM | |
| SCHEMBL13963484 | 0.75 | PNMT (0.43) | PNMTNOS3NOS2NOTUM | |
| SCHEMBL13303499 | 0.72 | MEN1 (0.40) | PNMTNOS3NOS2 | |
| SCHEMBL6860577 | 0.70 | — | — | |
| SCHEMBL2775298 | 0.67 | PNMT (0.37) | PNMTNOS3NOS2NOTUM | |
| SCHEMBL1823806 | 0.66 | NOS3 (0.39) | PNMTNOS3NOS2 | |
| SCHEMBL147105 | 0.66 | PNMT (0.53) | PNMT | |
| SCHEMBL15001031 | 0.64 | PNMT (0.43) | PNMTNOS3NOS2NOTUM | |
| SCHEMBL17970195 | 0.64 | PNMT (0.52) | PNMT | |
| SCHEMBL21093837 | 0.64 | PNMT (0.52) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113809-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |