Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.89 |
| ▸ | RAB9A | P51151 | 6/20 | 0.89 |
| ▸ | MAPT | P10636 | 1/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.82 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | FABP1 | P07148 | 1/20 | 0.61 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16589432 | 0.95 | PTPN1 (0.80) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL15450964 | 0.95 | NPC1 (0.80) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL10282271 | 0.95 | NPC1 (0.80) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL82305 | 0.94 | RAB9A (1.00) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| Iodide SCHEMBL30758618 | 0.93 | RAB9A (0.96) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL15214314 | 0.91 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL25491824 | 0.91 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL17066707 | 0.91 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL25970267 | 0.91 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL18085798 | 0.91 | PTPN1 (1.00) | NPC1RAB9AMAPTSMN1; SMN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265346-A1 | LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-08-24 | — | — | US | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | NPC1 1158/4885RAB9A 3923/4885MAPT 1215/4885 |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | NPC1 1158/4885RAB9A 3923/4885MAPT 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.