Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22540076 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL21433610 | 0.86 | GAA (0.55) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL21433611 | 0.86 | GAA (0.55) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL1843216 | 0.85 | GAA (0.68) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL1843219 | 0.85 | GAA (0.68) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL5705557 | 0.85 | GAA (0.68) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL30240785 | 0.85 | GAA (0.68) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL21433602 | 0.81 | GAA (0.47) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL21433603 | 0.81 | GAA (0.47) | KDM4EALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL6633882 | 0.78 | KMT2A (0.56) | KDM4EALDH1A1SMN1; SMN2GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171744-A1 | TIRE RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| EP-3722360-A1 | TIRE RUBBER COMPOSITION AND TIRE | Bridgestone Corporation (JP) | 2020-10-14 | — | — | EP | disclosed |