Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 17/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 10/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486163 | 1.00 | S1PR1 (0.42) | S1PR1F11KLKB1F9KLK1 | |
| SCHEMBL23486855 | 0.90 | MAPT (0.40) | S1PR1F11KLKB1 | |
| SCHEMBL30680266 | 0.90 | MAPT (0.40) | S1PR1F11KLKB1 | |
| SCHEMBL23486170 | 0.90 | MAPT (0.40) | S1PR1F11KLKB1 | |
| SCHEMBL30680299 | 0.87 | MEN1 (0.41) | — | |
| SCHEMBL29758118 | 0.86 | F11 (0.52) | S1PR1F11KLKB1F9KLK1 | |
| SCHEMBL23466397 | 0.86 | F11 (0.52) | S1PR1F11KLKB1F9KLK1 | |
| SCHEMBL23466398 | 0.86 | F11 (0.52) | S1PR1F11KLKB1F9KLK1 | |
| SCHEMBL3634248 | 0.84 | F11 (0.57) | F11KLKB1 | |
| SCHEMBL23486171 | 0.81 | CAPN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |