Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 11/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680266 | 1.00 | MAPT (0.40) | MAPTNPSR1MEN1KMT2AS1PR1 | |
| SCHEMBL23486855 | 1.00 | MAPT (0.40) | MAPTNPSR1MEN1KMT2AS1PR1 | |
| SCHEMBL23486163 | 0.90 | S1PR1 (0.42) | S1PR1F11KLKB1 | |
| SCHEMBL23486162 | 0.90 | S1PR1 (0.42) | S1PR1F11KLKB1 | |
| SCHEMBL30680304 | 0.88 | F11 (0.47) | MAPTNPSR1MEN1KMT2AS1PR1 | |
| SCHEMBL29139611 | 0.88 | F11 (0.47) | MAPTNPSR1MEN1KMT2AS1PR1 | |
| SCHEMBL23486634 | 0.88 | F11 (0.47) | MAPTNPSR1MEN1KMT2AS1PR1 | |
| SCHEMBL23486793 | 0.83 | MAPT (0.44) | MAPTNPSR1MEN1KMT2AS1PR1 | |
| SCHEMBL30680299 | 0.81 | MEN1 (0.41) | MEN1KMT2AKDM4E | |
| SCHEMBL23486357 | 0.80 | FPR2 (0.42) | MAPTNPSR1MEN1KMT2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |