SCHEMBL23486248

SCHEMBL23486248

O=C(O)CC[n+]1ccc(-c2nc3cccnc3s2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 5/20 0.49
LMNA P02545 3/20 0.49
THRB P10828 1/20 0.49
NPC1 O15118 8/20 0.49
RAB9A P51151 8/20 0.49
KDM4E B2RXH2 8/20 0.49
ALDH1A1 P00352 5/20 0.49
GLA P06280 3/20 0.49
GAA P10253 2/20 0.49
RUNX1 Q01196 2/20 0.49
CBFB Q13951 2/20 0.49
MAPT P10636 5/20 0.48
HPGD P15428 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
HSD17B10 Q99714 3/20 0.48
HTT P42858 3/20 0.48
MEN1 O00255 2/20 0.48
TSHR P16473 2/20 0.48
KMT2A Q03164 2/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23486246 0.82 S1PR1 (0.37) TP53LMNATHRBNPC1RAB9A
SCHEMBL23486136 0.82 PTGDR2 (0.34) TP53LMNATHRBNPC1RAB9A
SCHEMBL23486258 0.82 KDM4E (0.52) LMNANPC1RAB9AKDM4EALDH1A1
SCHEMBL23486270 0.81 KDM4E (0.37) LMNANPC1RAB9AKDM4EALDH1A1
SCHEMBL23197341 0.78 KDM4E (0.34) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL24795860 0.77 NPC1 (0.56) TP53LMNATHRBNPC1RAB9A
Bromide SCHEMBL23163322 0.77 KDM4E (0.34) KDM4EALDH1A1POLB
Hydrochloric Acid SCHEMBL23163911 0.77 PTGDR2 (0.33) KDM4EALDH1A1POLB
SCHEMBL13998684 0.75 KDM4E (0.61) TP53LMNATHRBNPC1RAB9A
SCHEMBL23196663 0.75 PTGDR2 (0.33) KDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed