SCHEMBL23486246

SCHEMBL23486246

O=C(O)CC[n+]1ccc(-c2nc3cncnc3s2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.37
TP53 P04637 4/20 0.34
LMNA P02545 4/20 0.34
THRB P10828 1/20 0.34
KDM4E B2RXH2 7/20 0.34
NPC1 O15118 5/20 0.33
RAB9A P51151 5/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
GAA P10253 2/20 0.33
POLB P06746 2/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
STAT1 P42224 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL23458508 0.92 S1PR1 (0.38) S1PR1TP53LMNATHRBMAPT
SCHEMBL23486158 0.87 RAB9A (0.38) TP53LMNATHRBKDM4ENPC1
Bromide SCHEMBL23458436 0.86 RAB9A (0.38) TP53LMNATHRBKDM4ENPC1
SCHEMBL23486248 0.82 TP53 (0.49) TP53LMNATHRBKDM4ENPC1
SCHEMBL23458511 0.82 S1PR1 (0.33) S1PR1MAPT
SCHEMBL23486249 0.81 KDM4E (0.34) LMNAKDM4ENPC1RAB9AALDH1A1
Hydrochloric Acid SCHEMBL23458577 0.80 KDM4E (0.33) LMNAKDM4ENPC1RAB9AALDH1A1
SCHEMBL23486136 0.77 PTGDR2 (0.34) TP53LMNATHRBKDM4ENPC1
SCHEMBL23197341 0.76 KDM4E (0.34) S1PR1KDM4EMAPTALDH1A1HPGD
SCHEMBL1924304 0.75 MAOB (0.46) LMNAKDM4ENPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed