SCHEMBL23486136

SCHEMBL23486136

O=C(O)CC[n+]1ccc(-c2nc3nccnc3s2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 5/20 0.34
KDM4E B2RXH2 4/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
RUNX1 Q01196 1/20 0.33
CBFB Q13951 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
ADORA3 P0DMS8 3/20 0.32
ADORA2A P29274 3/20 0.32
ADORA1 P30542 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23486270 0.83 KDM4E (0.37) PTGDR2KDM4EPOLBALDH1A1NPC1
SCHEMBL23486248 0.82 TP53 (0.49) KDM4EPOLBALDH1A1NPC1GLA
SCHEMBL23197341 0.80 KDM4E (0.34) PTGDR2KDM4EPOLBALDH1A1PPARG
Bromide SCHEMBL23163322 0.79 KDM4E (0.34) PTGDR2KDM4EPOLBALDH1A1PPARG
Hydrochloric Acid SCHEMBL23163911 0.79 PTGDR2 (0.33) PTGDR2KDM4EPOLBALDH1A1PPARG
Hydrochloric Acid SCHEMBL23458577 0.79 KDM4E (0.33) PTGDR2KDM4EPOLBALDH1A1NPC1
SCHEMBL23486269 0.77 KDM4E (0.37) KDM4EALDH1A1NPC1GLAGAA
SCHEMBL23196663 0.77 PTGDR2 (0.33) PTGDR2KDM4EPOLBALDH1A1PPARG
SCHEMBL23486246 0.77 S1PR1 (0.37) PTGDR2KDM4EPOLBALDH1A1NPC1
SCHEMBL24796218 0.74 ADORA3 (0.47) ALDH1A1ADORA3ADORA2AADORA1CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed