SCHEMBL23486705

SCHEMBL23486705

Cc1ccc(NC(=O)NS(=O)(=O)C2CC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.53
NPC1 O15118 4/20 0.53
EPHX1 P07099 1/20 0.53
TP53 P04637 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
CA14 Q9ULX7 1/20 0.52
PTPN7 P35236 1/20 0.51
LMNA P02545 1/20 0.51
PPARG P37231 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NR2E3 Q9Y5X4 1/20 0.50
NCOR2 Q9Y618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20118984 0.82 NPC1 (0.57) RAB9ANPC1RXFP1ALDH1A1MEN1
SCHEMBL5935470 0.80 ACP1 (0.53) RAB9ANPC1EPHX1TP53CA12
SCHEMBL8091184 0.78 RAB9A (0.57) RAB9ANPC1EPHX1CA12CA1
SCHEMBL8091213 0.78 RAB9A (0.57) RAB9ANPC1EPHX1TP53CA12
SCHEMBL8083387 0.78 RAB9A (0.57) RAB9ANPC1EPHX1CA12CA1
SCHEMBL19971761 0.78 CA1 (0.56) RAB9ANPC1TP53CA12CA1
SCHEMBL23486690 0.78 CA12 (0.59) RAB9ANPC1TP53CA12CA1
SCHEMBL19505872 0.77 ACP1 (0.57) RAB9AEPHX1TP53CA12CA1
SCHEMBL8095024 0.77 RAB9A (0.60) RAB9ANPC1EPHX1TP53CA12
SCHEMBL8089942 0.77 RAB9A (0.56) RAB9ANPC1EPHX1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110076-A1 OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 深圳信立泰药业股份有限公司 2021-06-10 WO disclosed