Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719326 | 0.84 | — | — | |
| SCHEMBL14311865 | 0.80 | ALDH1A1 (0.33) | POLBALDH1A1NPC1LMNAKDM4E | |
| SCHEMBL4766675 | 0.78 | FAAH (0.38) | POLBALDH1A1NPC1LMNAKDM4E | |
| SCHEMBL10805112 | 0.78 | NPC1 (0.36) | POLBALDH1A1NPC1LMNAKDM4E | |
| SCHEMBL674966 | 0.76 | — | — | |
| SCHEMBL177823 | 0.76 | — | — | |
| SCHEMBL7737389 | 0.76 | ALDH1A1 (0.33) | POLBALDH1A1NPC1 | |
| SCHEMBL11576147 | 0.76 | ALDH1A1 (0.31) | POLBALDH1A1NPC1 | |
| SCHEMBL4792344 | 0.76 | ALDH1A1 (0.35) | POLBALDH1A1NPC1 | |
| SCHEMBL21293730 | 0.74 | TDP1 (0.37) | ALDH1A1NPC1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101704-A1 | PROCESS FOR PREPARING (4S, 6S)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO-[2,3-B]THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE AND ITS INTERMEDIATES | MICRO LABS LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |
| US-4448719-A | TEXTILES; COLORFAST | CIBA-GEIGY CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4082739-A | FIBRE-REACTIVE DYESTUFF CONTAINING A BIS-TRIAZINYLAMINO | CIBA-GEIGY AG (CH) | 1978-04-04 | — | — | US | disclosed |
| US-3947407-A | ANTHRAQUINONE DYE | CIBA-GEIGY AG (CH) | 1976-03-30 | — | — | US | disclosed |