SCHEMBL23488337

SCHEMBL23488337

COC(=O)/C=C/c1ccc(COc2cc(OC)c(C(=O)N[C@H]3[C@@H](OC)O[C@H](CO)[C@@H](O)[C@@H]3O)cc2Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.53
CA9 Q16790 4/20 0.53
SNCA P37840 1/20 0.45
CA1 P00915 3/20 0.42
HK1 P19367 1/20 0.41
HK2 P52789 1/20 0.41
PTPN1 P18031 1/20 0.40
CA12 O43570 2/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LDHA P00338 1/20 0.38
AKR1B1 P15121 1/20 0.37
DPP4 P27487 1/20 0.37
LGALS8 O00214 1/20 0.37
PTGS1 P23219 1/20 0.37
LGALS3 P17931 1/20 0.37
ABCC8 Q09428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488731 0.94 CA2 (0.53) CA2CA9SNCACA1HK1
SCHEMBL23488737 0.88 SNCA (0.45) CA2CA9SNCACA1PTPN1
SCHEMBL23488456 0.87 CA2 (0.47) CA2CA9CA1LGALS8LGALS3
SCHEMBL23488216 0.85 CA2 (0.51) CA2CA9SNCACA1HK1
SCHEMBL23488495 0.85 CA2 (0.44) CA2CA9CA1MEN1KMT2A
SCHEMBL23488228 0.85 CA2 (0.44) CA2CA9CA1MEN1KMT2A
SCHEMBL23488735 0.85 CA2 (0.48) CA2CA9SNCACA1HK1
SCHEMBL23488749 0.84 CA2 (0.45) CA2CA9CA1MEN1KMT2A
SCHEMBL23488357 0.84 CA2 (0.45) CA2CA9CA1MEN1KMT2A
SCHEMBL23488230 0.81 CA2 (0.42) CA2CA9CA1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 CA2 1099/4885CA9 906/4885SNCA 4766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.