Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488210 | 0.99 | KLK7 (0.38) | KLK7KLK5CYP3A4SIRT2SIRT1 | |
| SCHEMBL23488530 | 0.98 | KLK7 (0.38) | KLK7KLK5CYP3A4SIRT2SIRT1 | |
| SCHEMBL23488345 | 0.98 | KLK7 (0.39) | KLK7KLK5CYP3A4SIRT2SIRT1 | |
| SCHEMBL23488360 | 0.94 | KLK7 (0.37) | KLK7KLK5SIRT2SIRT1SIRT3 | |
| SCHEMBL23488769 | 0.94 | KLK7 (0.37) | KLK7KLK5LGALS9LGALS1LGALS3 | |
| SCHEMBL23488330 | 0.93 | LGALS3 (0.36) | KLK7KLK5LGALS9LGALS1LGALS3 | |
| SCHEMBL23488371 | 0.92 | KLK7 (0.38) | KLK7KLK5SIRT2SIRT1SIRT3 | |
| SCHEMBL23488696 | 0.91 | KLK7 (0.37) | KLK7KLK5CYP3A4SIRT2SIRT1 | |
| SCHEMBL23488608 | 0.91 | KLK7 (0.37) | KLK7KLK5CYP3A4SIRT2SIRT1 | |
| SCHEMBL23488580 | 0.89 | LGALS3 (0.36) | CYP3A4LGALS9LGALS1LGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | KLK7 2859/4885KLK5 3345/4885CYP3A4 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.