SCHEMBL23488478

SCHEMBL23488478

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1OC(=O)c1cc(Cl)c(OCCc2cccc(Cl)c2)c(Cl)c1C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 5/20 0.44
LGALS9 O00182 1/20 0.44
LGALS1 P09382 1/20 0.44
LGALS7; LGALS7B P47929 1/20 0.44
LGALS4 P56470 4/20 0.43
LGALS8 O00214 3/20 0.40
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
MAOB P27338 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
FGF1 P05230 1/20 0.35
VEGFA P15692 1/20 0.35
SLC5A2 P31639 3/20 0.34
SLC5A1 P13866 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488473 0.92 LGALS3 (0.43) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488747 0.91 LGALS3 (0.45) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488684 0.90 LGALS3 (0.47) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488287 0.86 LGALS3 (0.47) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488619 0.86 LGALS3 (0.47) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488524 0.84 LGALS3 (0.44) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488552 0.81 LGALS3 (0.41) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488303 0.81 LGALS3 (0.46) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488753 0.80 LGALS3 (0.41) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4
SCHEMBL23488249 0.78 LGALS3 (0.47) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS3 156/4885LGALS9 106/4885LGALS1 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.