Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23455503 | 0.86 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL6777924 | 0.86 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL6777923 | 0.86 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL23489291 | 0.85 | KMT2A (0.50) | ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL308570 | 0.79 | ALDH1A1 (0.77) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7975430 | 0.77 | ALDH1A1 (0.72) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL983433 | 0.77 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL863169 | 0.75 | RAB9A (0.71) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11654124 | 0.75 | RAB9A (0.71) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL6242208 | 0.73 | RAB9A (0.84) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-20 | — | — | US | disclosed |
| US-20210171455-A1 | ALPHA-5 BETA-1 INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171455-A1 | ALPHA-5 BETA-1 INHIBITORS | SCN5A, PSMA5, API5 | ALDH1A1 227/4885RAB9A 2227/4885NPC1 651/4885 |
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | SCN5A, PSMA5, API5 | ALDH1A1 227/4885RAB9A 2227/4885NPC1 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.