Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345794 | 0.86 | TRPA1 (0.59) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL305074 | 0.80 | CDK1 (0.65) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28738145 | 0.78 | TRPA1 (0.55) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL56556 | 0.78 | TRPA1 (1.00) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30290839 | 0.78 | TRPA1 (1.00) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL18768241 | 0.78 | TRPA1 (0.43) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL17548948 | 0.77 | MAPT (0.54) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19315909 | 0.76 | TRPA1 (0.42) | TRPA1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL19497948 | 0.75 | MCL1 (0.55) | TRPA1KDM4EHSD17B10CYP3A4CNR1 | |
| SCHEMBL12693941 | 0.74 | TRPA1 (0.41) | TRPA1ALOX12KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171492-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171492-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | TRPA1 1736/4885ALOX12 2656/4885KDM4E 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.