SCHEMBL305074

SCHEMBL305074

CCc1ccc(O)c(C=O)c1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.65
TRPA1 O75762 1/20 0.57
ERN1 O75460 11/20 0.52
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
HTT P42858 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NT5E P21589 1/20 0.47
POLB P06746 1/20 0.45
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7094408 0.91 CDK1 (0.65) CDK1TRPA1ERN1KDM4EUSP2
SCHEMBL29953951 0.85 CDK1 (0.71) CDK1ERN1GAANT5EPOLB
SCHEMBL304505 0.85 CDK1 (0.71) CDK1ERN1GAANT5EPOLB
SCHEMBL1527080 0.84 TRPA1 (0.57) CDK1TRPA1KDM4EUSP2ALDH1A1
SCHEMBL1276254 0.84 CDK1 (0.51) CDK1TRPA1ERN1KDM4EUSP2
SCHEMBL283097 0.83 CDK1 (0.69) CDK1ERN1NT5ETRIM24TRIM33
SCHEMBL19757236 0.83 CDK1 (0.81) CDK1ERN1ALOX15NT5ETRIM24
SCHEMBL305915 0.82 CDK1 (0.77) CDK1ERN1ALDH1A1ALOX15HTT
SCHEMBL29657596 0.82 CDK1 (0.67) CDK1ERN1NT5ETRIM24TRIM33
SCHEMBL5528390 0.82 CDK1 (0.67) CDK1ERN1NT5ETRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4587669-B2 2010-11-24 JP claimed
JP-2005509662-A 2005-04-14 JP claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
EP-0721482-B1 ADHESION PROMOTER FOR PVC COMPOUNDS DU PONT (US) 1997-11-05 EP claimed
EP-0378265-B1 Low-temperature curable compositions based upon polyaromatic aldehyde group-containing compounds and ketiminized polyamino compounds AKZO NOBEL NV (NL) 1994-06-08 EP claimed
US-5219954-A Improved ductility, flexural stiffness, modulus and tensile strength SHELL OIL COMPANY (US) 1993-06-15 US claimed
CN-121181505-A Preparation method of 5-ethylbenzofuran-3-carboxylic acid 凯美克(上海)医药科技有限公司 2025-12-23 CN disclosed
CN-115710228-B Pyrazole benzophenone compound and preparation method and application thereof 江西科技师范大学 2024-12-13 CN disclosed
US-20230129381-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF ANTICANCER-DRUG RESISTANT CANCERS THE GEORGE WASHINGTON UNIVERSITY 2023-04-27 US disclosed
CN-115710228-A Pyrazole benzophenone compound and preparation method and application thereof 江西科技师范大学 2023-02-24 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-1044474-A Composition based on the low-temperature curable of the polyamino compound of compound that contains many aromatic aldehydes base and ketoimineization AKZO NV (NL) 1990-08-08 CN disclosed
EP-0378265-A1 Low-temperature curable compositions based upon polyaromatic aldehyde group-containing compounds and ketiminized polyamino compounds Akzo Nobel N.V. (NL) 1990-07-18 EP disclosed
WO-1983000333-A1 ANTI-HYPERTENSOR, HETEROCYCLICALLY DI-ORTHOSUBSTITUTED PHENOLS TEULON, JEAN-MARIE 1983-02-03 WO disclosed
EP-0070779-A2 Di-ortho-substituted phenols of which one of the substitutions is a heterocycle, process for their preparation, anti-hypertensive medicines containing them and synthesis intermediates CARPIBEM (CENTRE D'ACTIVITE ET DE RECHERCHE PHARMACEUTIQUE INDUSTRIELLE BIOLOGIQUE ET MEDICALE) Société Anonyme dite: (FR) 1983-01-26 EP disclosed
US-4002423-A Benzofuran derivatives process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed
US-3976663-A INSECTICIDE THE PROCTER & GAMBLE COMPANY (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 CDK1 4235/4885TRPA1 67/4885ERN1 4830/4885
US-20230129381-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF ANTICANCER-DRUG RESISTANT CANCERS TP53, ANXA5, MCL1 CDK1 586/4885TRPA1 4652/4885ERN1 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.