SCHEMBL23494666

SCHEMBL23494666

CC(C)(C)C1CCC(NC(=O)c2cc(NC(=O)C3CCC(C(C)(C)C)CC3)cc(NC(=O)C3CCC(C(C)(C)C)CC3)c2)CC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.57
HSD17B10 Q99714 1/20 0.49
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.45
ACKR3 P25106 1/20 0.43
GAA P10253 1/20 0.43
EPHX1 P07099 1/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMYD3 Q9H7B4 2/20 0.41
HPGDS O60760 2/20 0.41
LIPE Q05469 1/20 0.41
NAMPT P43490 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23494714 1.00 GLA (0.57) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494665 1.00 GLA (0.57) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494701 1.00 GLA (0.57) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494739 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494674 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494755 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494704 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494747 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494707 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG
SCHEMBL23494670 0.92 GLA (0.49) GLAHSD17B10RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4317128-B1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2025-07-23 EP claimed
US-12358864-B2 Trisamide compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2025-07-15 US claimed
CN-117756661-A Triamide compound and composition comprising same 美利肯公司 2024-03-26 CN claimed
EP-4317128-A2 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2024-02-07 EP claimed
EP-4073029-B1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2024-01-31 EP claimed
CN-115066413-B Triamide compound and composition comprising same 美利肯公司 2024-01-09 CN claimed
US-20230331660-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2023-10-19 US claimed
US-11724983-B2 Trisamide compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2023-08-15 US claimed
EP-4073029-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2022-10-19 EP claimed
CN-115066413-A Triamide compounds and compositions comprising the same 美利肯公司 2022-09-16 CN claimed
US-20210179540-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2021-06-17 US claimed
WO-2021119633-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY (US) 2021-06-17 WO claimed
EP-4317128-B1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2025-07-23 EP disclosed
US-12358864-B2 Trisamide compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2025-07-15 US disclosed
CN-117756661-A Triamide compound and composition comprising same 美利肯公司 2024-03-26 CN disclosed
EP-4317128-A2 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2024-02-07 EP disclosed
EP-4073029-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME Milliken & Company (US) 2022-10-19 EP disclosed
CN-115066413-A Triamide compounds and compositions comprising the same 美利肯公司 2022-09-16 CN disclosed
US-20210179540-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2021-06-17 US disclosed
WO-2021119633-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY (US) 2021-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11724983-B2 Trisamide compounds and compositions comprising the same PTAR1, TIPRL, TCOF1 GLA 612/4885HSD17B10 3171/4885RXRA 2448/4885
US-20230331660-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME PTAR1, TIPRL, TCOF1 GLA 612/4885HSD17B10 3171/4885RXRA 2448/4885
US-20210179540-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME PTAR1, TIPRL, TCOF1 GLA 612/4885HSD17B10 3171/4885RXRA 2448/4885
US-12358864-B2 Trisamide compounds and compositions comprising the same PTAR1, TIPRL, TCOF1 GLA 612/4885HSD17B10 3171/4885RXRA 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.