Methacrylic Acid

Methacrylic Acid

SCHEMBL2349705

C=C(C)C(=O)O.CC(C)(NCCO)c1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 1/20 0.42
DPP4 P27487 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
KCNN4 O15554 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2346951 0.87 KCNN4 (0.47) KDM4EKMT2AMEN1LMNAPOLB
Acrylic Acid SCHEMBL2354873 0.84 ALDH1A1 (0.41) KDM4EKMT2AMEN1LMNAPOLB
Methacrylic Acid SCHEMBL2345825 0.79 BACE1 (0.44) KDM4EKMT2AMEN1DPP4CYP2C19
SCHEMBL4401452 0.78 HTT (0.41) KDM4EKMT2AMEN1POLBDPP4
SCHEMBL9166467 0.77 ALDH1A1 (0.44) KMT2ALMNADPP4CYP2C19HIF1A
Hydrochloric Acid SCHEMBL166561 0.77 HTT (0.40) KDM4EKMT2AMEN1POLBDPP4
Bromide SCHEMBL3858373 0.77 HTT (0.40) KDM4EKMT2AMEN1POLBDPP4
Iodide SCHEMBL3858235 0.77 HTT (0.40) KDM4EKMT2AMEN1POLBDPP4
Methacrylic Acid SCHEMBL27522954 0.76 SSTR4 (0.44) KDM4EKMT2ALMNACYP2C19HIF1A
Methacrylic Acid SCHEMBL8850862 0.75 CYP2C19 (0.53) KDM4EKMT2AMEN1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP claimed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US claimed
EP-3144332-B1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2020-10-21 EP claimed
EP-3481878-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM Evonik Degussa GmbH (DE) 2019-05-15 EP claimed
WO-2018013590-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK DEGUSSA GMBH (DE) 2018-01-18 WO claimed
US-20180009930-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2018-01-11 US claimed
EP-3144332-A1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-03-22 EP claimed
US-20140042361-A1 TRIMER CATALYSTS WITH IMPROVED PROCESSABILITY AND SURFACE CURE EVONIK OPERATIONS GMBH (DE) 2014-02-13 US claimed
US-20140005037-A1 TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2014-01-02 US claimed
US-20070259982-A1 Trimer catalysts with improved processability and surface cure EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
US-20070259773-A1 Trimer catalyst additives for improving foam processability EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP disclosed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US disclosed
EP-3310827-B1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS EVONIK OPERATIONS GMBH (DE) 2021-01-06 EP disclosed
US-20070259773-A1 Trimer catalyst additives for improving foam processability EVONIK OPERATIONS GMBH (DE) 2007-11-08 US disclosed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1852448-A2 New trimerization catalysts from sterically hindered salts Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed