Acrylic Acid

Acrylic Acid

SCHEMBL2354873

C=CC(=O)O.CC(C)(NCCO)c1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
DPP4 P27487 1/20 0.39
TSHR P16473 1/20 0.39
HIF1A Q16665 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2346951 0.87 KCNN4 (0.47) ALDH1A1CYP2C19CYP3A4KMT2AKDM4E
Methacrylic Acid SCHEMBL2349705 0.84 KDM4E (0.42) ALDH1A1CYP2C19KMT2AKDM4EMEN1
Acrylic Acid SCHEMBL10588857 0.82 NAAA (0.46) ALDH1A1HDAC3HDAC1HDAC2HTT
Acrylic Acid SCHEMBL2348761 0.79 BACE1 (0.44) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL2880890 0.78 THRB (0.50) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
Bromide SCHEMBL3857939 0.77 THRB (0.49) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
Hydrochloric Acid SCHEMBL8863135 0.77 TGM2 (0.47) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
Iodide SCHEMBL3861985 0.77 THRB (0.49) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
Hydrochloric Acid SCHEMBL718579 0.77 THRB (0.49) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
Bromide SCHEMBL28188129 0.75 KCNN4 (0.44) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP claimed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US claimed
EP-3144332-B1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2020-10-21 EP claimed
EP-3481878-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM Evonik Degussa GmbH (DE) 2019-05-15 EP claimed
WO-2018013590-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK DEGUSSA GMBH (DE) 2018-01-18 WO claimed
US-20180009930-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2018-01-11 US claimed
EP-3144332-A1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-03-22 EP claimed
EP-1852450-B1 New trimer catalyst additives for improving foam processability AIR PROD & CHEM (US) 2016-12-14 EP claimed
US-20140042361-A1 TRIMER CATALYSTS WITH IMPROVED PROCESSABILITY AND SURFACE CURE EVONIK OPERATIONS GMBH (DE) 2014-02-13 US claimed
US-20140005037-A1 TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2014-01-02 US claimed
US-20070259773-A1 Trimer catalyst additives for improving foam processability EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
US-20070259982-A1 Trimer catalysts with improved processability and surface cure EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP disclosed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US disclosed
EP-3310827-B1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS EVONIK OPERATIONS GMBH (DE) 2021-01-06 EP disclosed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1852448-A2 New trimerization catalysts from sterically hindered salts Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed