Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | PCNA | P12004 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70972 | 0.93 | FFAR1 (0.70) | FFAR1FFAR4HDAC3MAPK1ADRA1A | |
| SCHEMBL3424976 | 0.89 | FFAR1 (0.77) | FFAR1FFAR4SRD5A2PCNA | |
| SCHEMBL284671 | 0.89 | SMN1; SMN2 (0.69) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL27615885 | 0.88 | FFAR1 (0.80) | FFAR1FFAR4HDAC3MAPK1ADRA1A | |
| Hydroxyphenyl Propionic Acid SCHEMBL2523914 | 0.85 | HDAC3 (0.64) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL418561 | 0.83 | MAPT (0.68) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL31522354 | 0.82 | MAPT (0.71) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL1832377 | 0.82 | MAPT (0.71) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL28968198 | 0.82 | MAPT (0.66) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL9662554 | 0.82 | MAPT (0.71) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476399-B2 | Biocompatible polymers for medical devices | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-07-02 | — | — | US | disclosed |
| US-20130085238-A1 | BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-04-04 | — | — | US | disclosed |
| US-8252887-B2 | Biocompatible polymers for medical devices | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2349981-A1 | BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES | Rutgers, The State University of New Jersey (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20100234555-A1 | BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES | RUTGERS, THE STATE UNIVERSITY (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2010042918-A1 | BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234555-A1 | BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES | ECPAS, PTGIR, RXFP1 | FFAR1 827/4885FFAR4 1951/4885HDAC3 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.