SCHEMBL70972

SCHEMBL70972

O=C(O)CCCc1ccc(Oc2ccc(CCCC(=O)O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.70
SMN1; SMN2 Q16637 2/20 0.64
HDAC3 O15379 1/20 0.64
MAPK1 P28482 1/20 0.64
ADRA1A P35348 1/20 0.64
HDAC4 P56524 1/20 0.64
SLC6A3 Q01959 1/20 0.64
HDAC1 Q13547 1/20 0.64
HDAC7 Q8WUI4 1/20 0.64
HDAC2 Q92769 1/20 0.64
HDAC10 Q969S8 1/20 0.64
HDAC11 Q96DB2 1/20 0.64
HDAC8 Q9BY41 1/20 0.64
HDAC6 Q9UBN7 1/20 0.64
HDAC9 Q9UKV0 1/20 0.64
HDAC5 Q9UQL6 1/20 0.64
SRD5A2 P31213 1/20 0.60
HSD17B10 Q99714 1/20 0.59
FFAR4 Q5NUL3 5/20 0.58
CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27615885 0.94 FFAR1 (0.80) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL2349797 0.93 FFAR1 (0.62) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL10276941 0.88 FFAR1 (0.75) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL27615872 0.88 FFAR1 (0.60) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
Apteniol A SCHEMBL16431559 0.88 FFAR1 (0.89) FFAR1SRD5A2FFAR4LMNA
SCHEMBL6208836 0.87 SMN1; SMN2 (0.82) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL69789 0.85 SMN1; SMN2 (0.78) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL10327442 0.85 MAPT (0.57) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL503646 0.85 ALOX5 (0.68) FFAR1SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL2774842 0.82 FFAR1 (1.00) FFAR1SRD5A2FFAR4PLAAT3PLAAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 FFAR1 986/4885SMN1; SMN2 4357/4885HDAC3 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.