Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 5/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500472 | 0.89 | DPP4 (0.57) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL17270378 | 0.88 | DPP4 (0.48) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL27789261 | 0.84 | DPP4 (0.52) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL5422476 | 0.82 | ADRB2 (0.51) | DPP4CHRM2DRD1KMT2AALDH1A1 | |
| SCHEMBL4774919 | 0.81 | DPP4 (0.44) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL27788932 | 0.79 | DPP4 (0.41) | DPP4CHRM2DRD1MEN1KMT2A | |
| SCHEMBL27344629 | 0.79 | DPP4 (0.48) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL17537004 | 0.78 | DPP4 (0.47) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL16469268 | 0.78 | DPP4 (0.38) | DPP4CHRM2DRD1ALDH1A1POLB | |
| SCHEMBL22774763 | 0.78 | DPP4 (0.38) | DPP4CHRM2DRD1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116451-A1 | HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-06-17 | — | — | WO | disclosed |