Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 3/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789261 | 0.86 | DPP4 (0.52) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL27788937 | 0.86 | DPP4 (0.40) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL17270378 | 0.84 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL5422476 | 0.80 | ADRB2 (0.51) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL500472 | 0.80 | DPP4 (0.57) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL23498281 | 0.79 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL10996251 | 0.78 | LMNA (0.48) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL17537004 | 0.77 | DPP4 (0.47) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL4774919 | 0.75 | DPP4 (0.44) | DPP4CHRM2DRD1KDM4EALDH1A1 | |
| SCHEMBL30510604 | 0.74 | DPP4 (0.37) | DPP4CHRM2DRD1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101792443-A | Fluoro-carbostyril derivative as well as preparation method and application thereof | OKEANOS TECH CO LTD | 2010-08-04 | — | — | CN | claimed |
| CN-101792443-A | Fluoro-carbostyril derivative as well as preparation method and application thereof | OKEANOS TECH CO LTD | 2010-08-04 | — | — | CN | disclosed |