Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810315 | 0.87 | ALDH1A1 (0.42) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL23499073 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL23498802 | 0.82 | MAPT (0.42) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL23498937 | 0.80 | DRD4 (0.44) | SMN1; SMN2KDM4EALDH1A1RAB9APOLB | |
| SCHEMBL21809610 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL25091647 | 0.76 | NPC1 (0.41) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL23499048 | 0.76 | DRD4 (0.42) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL23498776 | 0.75 | POLB (0.40) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL23498847 | 0.75 | TSHR (0.38) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL21810028 | 0.74 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230107941-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. | 2023-04-06 | — | — | US | disclosed |
| WO-2021119081-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. (US) | 2021-06-17 | — | — | WO | disclosed |
| WO-2021119081-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. (US) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230107941-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | HAVCR2, COPB1, HDLBP | SMN1; SMN2 3117/4885KDM4E 3751/4885MAPT 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.