Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270258 | 0.92 | ALDH1A1 (0.60) | MCHR1TSHRSLC18A3ALDH1A1KDM4E | |
| SCHEMBL23501065 | 0.92 | CYP2D6 (0.55) | MCHR1SLC18A3ALDH1A1KDM4EMEN1 | |
| SCHEMBL6272336 | 0.92 | TSHR (0.60) | MCHR1TSHRSLC18A3ALDH1A1SIGMAR1 | |
| SCHEMBL8172117 | 0.86 | TSHR (0.54) | MCHR1TSHRSLC18A3ALDH1A1KDM4E | |
| SCHEMBL8231916 | 0.83 | SLC18A3 (0.60) | MCHR1TSHRSLC18A3ALDH1A1KDM4E | |
| SCHEMBL3559726 | 0.83 | MCHR1 (0.60) | MCHR1TSHRSLC18A3ALDH1A1KDM4E | |
| SCHEMBL6265377 | 0.81 | HTR1A (0.52) | MCHR1 | |
| SCHEMBL14197728 | 0.81 | TSHR (0.56) | MCHR1TSHRSLC18A3ALDH1A1KDM4E | |
| SCHEMBL28591860 | 0.81 | TSHR (0.56) | MCHR1TSHRSLC18A3ALDH1A1KDM4E | |
| SCHEMBL8180360 | 0.80 | MCHR1 (0.65) | MCHR1ALDH1A1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115413-A1 | NEUROMUSCULAR-BLOCKING DRUG AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2021-06-17 | — | — | WO | disclosed |
| WO-2021115413-A1 | NEUROMUSCULAR-BLOCKING DRUG AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2021-06-17 | — | — | WO | disclosed |