Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501601 | 0.78 | CYP2C9 (0.50) | KDM4EPOLBL3MBTL1ALDH1A1CYP2C9 | |
| SCHEMBL17803461 | 0.78 | HCAR2 (0.44) | HCAR2KDM4EPOLBALDH1A1ALOX15 | |
| SCHEMBL846024 | 0.76 | HCAR2 (0.50) | HCAR2KDM4EPOLBTDP1ALDH1A1 | |
| Formamide SCHEMBL28252276 | 0.75 | KDM4E (0.45) | HCAR2KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL4140207 | 0.75 | AGBL2 (0.41) | HCAR2KDM4EALDH1A1ERN1MEN1 | |
| SCHEMBL4121189 | 0.75 | HCAR2 (0.48) | HCAR2KDM4EPOLBL3MBTL1TDP1 | |
| SCHEMBL9504528 | 0.75 | HCAR2 (0.48) | HCAR2KDM4EPOLBTDP1ALDH1A1 | |
| SCHEMBL6052889 | 0.75 | HCAR2 (0.48) | HCAR2KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL30668508 | 0.75 | HCAR2 (0.48) | HCAR2KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL6626617 | 0.74 | ERN1 (0.46) | KDM4EALDH1A1ERN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |