SCHEMBL4121189

SCHEMBL4121189

Cc1ncc(C(=O)O)cc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.48
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MAPT P10636 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
CA3 P07451 1/20 0.46
SELL P14151 1/20 0.46
HPGD P15428 1/20 0.46
SELP P16109 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846024 0.81 HCAR2 (0.50) HCAR2KDM4EALDH1A1HSD17B10TDP1
SCHEMBL9504528 0.79 HCAR2 (0.48) HCAR2KDM4EALDH1A1HSD17B10TDP1
SCHEMBL6052889 0.79 HCAR2 (0.48) HCAR2KDM4EALDH1A1HSD17B10TDP1
SCHEMBL30668508 0.79 HCAR2 (0.48) HCAR2KDM4EALDH1A1HSD17B10TDP1
SCHEMBL14803342 0.79 KDM4E (0.52) KDM4EALDH1A1HSD17B10CA12CA1
SCHEMBL17703486 0.79 KDM4E (0.55) KDM4EALDH1A1HSD17B10CA12CA1
SCHEMBL27751624 0.78 KDM4E (0.50) HCAR2KDM4EALDH1A1HSD17B10CA12
SCHEMBL12845747 0.78 HCAR2 (0.47) HCAR2KDM4EALDH1A1HSD17B10TDP1
SCHEMBL7356328 0.78 KDM4E (0.47) HCAR2KDM4EALDH1A1HSD17B10MAPT
SCHEMBL10200753 0.78 TPMT (0.48) HCAR2KDM4EALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393290-B Preparation method of 3,4, 5-trimethylhydroquinone dialkanoate 万华化学集团股份有限公司 2023-03-24 CN claimed
CN-112156645-B Composite biological enzyme deodorant and preparation method thereof 柳州市宝净科技有限公司 2021-04-27 CN claimed
CN-112156645-A Composite biological enzyme deodorant and preparation method thereof 柳州市宝净科技有限公司 2021-01-01 CN claimed
CN-111393290-A Preparation method of 3,4, 5-trimethylhydroquinone dialkanoate 万华化学集团股份有限公司 2020-07-10 CN claimed
US-20090211346-A1 Methods for Detecting Alzheimer's Disease BG MEDICINE, INC. 2009-08-27 US claimed
EP-1869474-A1 METHODS FOR DETECTING ALZHEIMER'S DISEASE BG Medicine, Inc. (US) 2007-12-26 EP claimed
WO-2006099377-A1 METHODS FOR DETECTING ALZHEIMER'S DISEASE BG MEDICINE, INC. (US) 2006-09-21 WO claimed
US-20260007672-A1 INHIBITORS OF MPTP NRG THERAPEUTICS LTD (GB) 2026-01-08 US disclosed
US-12491185-B2 Inhibitors of mPTP NRG THERAPEUTICS LTD (GB) 2025-12-09 US disclosed
EP-4652162-A1 INHIBITORS OF MPTP NRG Therapeutics LTD (GB) 2025-11-26 EP disclosed
US-20250177397-A1 INHIBITORS OF MPTP NRG THERAPEUTICS LTD (GB) 2025-06-05 US disclosed
WO-2024153946-A1 INHIBITORS OF MPTP NRG THERAPEUTICS LTD (GB) 2024-07-25 WO disclosed
CN-111393290-B Preparation method of 3,4, 5-trimethylhydroquinone dialkanoate 万华化学集团股份有限公司 2023-03-24 CN disclosed
US-8404465-B2 Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks CELEXION, LLC (US) 2013-03-26 US disclosed
US-20130017593-A1 Biological Synthesis of Difunctional Hexanes and Pentanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2013-01-17 US disclosed
US-20120301950-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC 2012-11-29 US disclosed
US-8206986-B2 Methods for detecting Alzheimer's disease BG MEDICINE, INC. (US) 2012-06-26 US disclosed
US-20090211346-A1 Methods for Detecting Alzheimer's Disease BG MEDICINE, INC. 2009-08-27 US disclosed
EP-1869474-A1 METHODS FOR DETECTING ALZHEIMER'S DISEASE BG Medicine, Inc. (US) 2007-12-26 EP disclosed
WO-2006099377-A1 METHODS FOR DETECTING ALZHEIMER'S DISEASE BG MEDICINE, INC. (US) 2006-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12491185-B2 Inhibitors of mPTP PARK7, PINK1, SNCA HCAR2 1506/4885KDM4E 2432/4885ALDH1A1 415/4885
US-20250177397-A1 INHIBITORS OF MPTP PARK7, PINK1, SNCA HCAR2 1506/4885KDM4E 2432/4885ALDH1A1 415/4885
US-20260007672-A1 INHIBITORS OF MPTP PARK7, SNCA, CYC1 HCAR2 713/4885KDM4E 3133/4885ALDH1A1 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.