Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934024 | 1.00 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1KMT2AHCAR2 | |
| SCHEMBL31364801 | 0.83 | ATM (0.51) | ALDH1A1KDM4EMEN1KMT2ACYP2C9 | |
| SCHEMBL30811844 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AHCAR2 | |
| SCHEMBL17820066 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KDM4EMEN1KMT2AHCAR2 | |
| SCHEMBL3944146 | 0.71 | ALDH1A1 (0.66) | ALDH1A1KDM4EMEN1KMT2AHCAR2 | |
| SCHEMBL30366002 | 0.70 | APLNR (0.45) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL27991133 | 0.70 | APLNR (0.45) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL26145000 | 0.70 | KDM4E (0.52) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL51830 | 0.70 | HCAR2 (0.70) | ALDH1A1KDM4EMEN1KMT2AHCAR2 | |
| SCHEMBL21062029 | 0.69 | KDM4E (0.36) | ALDH1A1KDM4EMEN1KMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |