SCHEMBL23503172

SCHEMBL23503172

N#Cc1cccc(C#N)c1-c1cccc(-n2c3ccccc3c3c2ccc2c4ccccc4n(-c4ccccc4)c23)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 2/20 0.34
MAPK1 P28482 2/20 0.34
LMNA P02545 1/20 0.34
MAOA P21397 2/20 0.32
IL1R1 P14778 1/20 0.32
MAPT P10636 2/20 0.31
HIF1A Q16665 1/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23503028 1.00 L3MBTL1 (0.41) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503283 0.97 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503009 0.97 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503176 0.97 ATM (0.37) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503233 0.97 ATM (0.37) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503284 0.95 KDM4E (0.35) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503010 0.95 KDM4E (0.35) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503175 0.92 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503025 0.92 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23503201 0.92 KDM4E (0.42) L3MBTL1KDM4EATMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038117-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-15 US disclosed